CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 512 enrolled
Drug / intervention
Fluticasone Furoate 100mcg/ GW642444 (vilanterol) 25mcg +3 moredrug
Likely dose
Fluticasone Furoate 100mcg/ GW642444 (vilanterol) 25mcgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01323621
NCT01323621Phase 3Completed

A 12-week Study to Evaluate the 24-hour Pulmonary Function Profile of Fluticasone Furoate/Vilanterol (FF/VI) Inhalation Powder 100/25 mcg Once Daily Compared With Fluticasone Propionate/Salmeterol Inhalation Powder 250/50 mcg Twice Daily in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

GlaxoSmithKline·interventional·Posted Mar 25, 2011·Updated Feb 15, 2018

In Brief

A Phase 3 clinical trial evaluating Fluticasone Furoate 100mcg/ GW642444 (vilanterol) 25mcg, Fluticasone Propionate 250mcg / salmeterol 50mcg, and 2 other interventions for Pulmonary Disease, Chronic Obstructive. Completed, enrolled 512 participants across 51 sites in 6 countries.

Detailed Summary

The purpose of this study is to evaluate the 24-hour spirometry effect (FEV1) of FF/VI 100/25mcg once daily compared with Fluticasone Propionate/Salmeterol 250/50mcg twice daily over a 12-week treatment period in subjects with COPD.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesGermany, Italy, South Africa, Spain, Ukraine, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedMar 25, 2011
Enrollment StartMar 18, 2011
Primary CompletionJan 1, 2012
Study CompletionJan 24, 2012
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 15.3 years ago

Interventions

Fluticasone Furoate 100mcg/ GW642444 (vilanterol) 25mcgdrug

inhalation powder

Fluticasone Propionate 250mcg / salmeterol 50mcgdrug

inhalation powder

Double-dummy placebodrug

inhalation powder

Salbutamol as neededdrug

inhalation powder