CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 47 enrolled
Drug / intervention
oxaliplatin +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01338792
NCT01338792Phase 2Completed
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A Phase II Trial of Oxaliplatin and Pemetrexed in Hormone Refractory Prostate Cancer

University of Southern California·interventional·Posted Apr 20, 2011·Updated Mar 10, 2014

In Brief

A Phase 2 clinical trial evaluating oxaliplatin, pemetrexed disodium, and 4 other interventions for Hormone-resistant Prostate Cancer and Recurrent Prostate Cancer. Completed, enrolled 47 participants across 1 site.

Detailed Summary

This phase II trial studies how well giving oxaliplatin and pemetrexed disodium together works in treating patients with refractory hormone-resistant prostate cancer. Drugs used in chemotherapy, such as oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Pemetrexed disodium may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving oxaliplatin together with pemetrexed disodium may kill more tumor cells.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHormone-resistant Prostate Cancer, Recurrent Prostate Cancer
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI)

Timeline

Phase 2CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedApr 20, 2011
Enrollment StartJun 1, 2006
Primary CompletionDec 1, 2011
Study CompletionDec 1, 2012
TodayJul 2, 2026
Enrollment to primary: 5.5 yearsPosted 15.2 years ago

Interventions

oxaliplatindrug

Given IV

pemetrexed disodiumdrug

Given IV

questionnaire administrationother

Ancillary studies

laboratory biomarker analysisother

Correlative studies

reverse transcriptase-polymerase chain reactiongenetic

Correlative studies

polymorphism analysisgenetic

Correlative studies