CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 302 enrolled
Drug / intervention
Clopidogrel +2 moredrug
Likely dose
Clopidogrel 600mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01341964
NCT01341964Phase 4Completed
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Randomized Controlled Trial to Explore Interaction Between Aspirin and Clopidogrel in Stable Patients With Previous Myocardial Infarction or Coronary Artery Stent

Population Health Research Institute·interventional·Posted Apr 26, 2011·Updated Jul 27, 2023

In Brief

A Phase 4 clinical trial evaluating Clopidogrel and Aspirin for Drug Action Increased. Completed, enrolled 302 participants across 1 site.

Detailed Summary

Clopidogrel and aspirin are commonly used in combination to prevent heart attacks and to prevent blockage of stents. Both clopidogrel and aspirin work by preventing platelets (sticky cells that circulate in the blood) from forming blood clots in the arteries supplying oxygen to the heart and in stents. The investigators hypothesize that aspirin 325mg compared with aspirin 81 mg will increase blood levels of the active metabolite of clopidogrel in patients with a history of coronary artery disease who receive a 600mg loading dose of clopidogrel.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDrug Action Increased
CountriesCanada
Collaborators--

Timeline

Phase 4CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedApr 26, 2011
Enrollment StartMay 1, 2011
Primary CompletionApr 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 15.2 years ago

Interventions

Clopidogreldrug

600mg (2 pills)

Aspirindrug

325mg (1 pill)

Aspirindrug

81mg (1 pill)