CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 58 enrolled
Drug / intervention
diffusion tensor tractography neuronavigation and intraoperative subcortical stimulationprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01351337
NCT01351337N/ACompleted
CompareCT.gov

Clinical Efficiency of Motor Pathway Mapping Using Diffusion Tensor Imaging Tractography and Intraoperative Subcortical Stimulation in Cerebral Glioma Surgery

Huashan Hospital·interventional·Posted May 10, 2011·Updated Apr 20, 2015

In Brief

A clinical study evaluating diffusion tensor tractography neuronavigation and intraoperative subcortical stimulation for Glioma, Motor Pathway. Completed, enrolled 58 participants across 1 site.

Detailed Summary

Resection of brain tumors in eloquent areas involves the risk of postoperative motor deficits. For brain tumors within or adjacent to the eloquent area, maximizing tumor resection while preserving motor function is crucially important.we used DTI-based tractography to visualize the spatial relationship between brain lesions and the nearby pyramidal tract(PT) in patients with malignant brain tumors and confirmed functional connections of the illustrated PT by direct electrical stimulation. We evaluated the reliability of DTI-based tractography for PT mapping using intraoperative subcortical stimulation ) and the usefulness of the combination of two techniques.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGlioma, Motor Pathway
CountriesChina
CollaboratorsShanghai Municipal Science and Technology Commission

Timeline

N/ACompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedMay 10, 2011
Enrollment StartOct 1, 2008
Primary CompletionJun 1, 2009
Study CompletionFeb 1, 2013
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 15.1 years ago

Interventions

diffusion tensor tractography neuronavigation and intraoperative subcortical stimulationprocedure

All of the patients underwent tumor resection assisted with combined use of Diffusion tensor tractography-integrated functional neuronavigation and intraoperative subcortical stimulation