CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 170 enrolled
Drug / intervention
Action-focused problem-solving +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

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Search/NCT01356277
NCT01356277N/ACompleted
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TAKE-IT: Teen Adherence in Kidney Transplant Effectiveness of Intervention Trial

McGill University Health Centre/Research Institute of the McGill University Health Centre·interventional·Posted May 19, 2011·Updated Jul 18, 2018

In Brief

A clinical study evaluating Action-focused problem-solving and Electronic pillbox monitoring, dose reminders, and feedback for Kidney Transplantation and Medication Adherence. Completed, enrolled 170 participants across 8 sites in 2 countries.

Detailed Summary

The broad aim of the proposed study is to improve medication adherence in adolescent kidney transplant recipients. The investigators hypothesize that a multi-component intervention will improve medication adherence in the adolescent kidney transplant population. The specific aims are to determine, in a randomized clinical trial, the efficacy of a structured, multi-component intervention in improving adherence to anti-rejection medications and graft outcomes, and to identify characteristics of healthcare systems that are independently associated with adherence.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKidney Transplantation, Medication Adherence
CountriesCanada, United States
CollaboratorsChildren's Hospital of Philadelphia, Children's Hospital Medical Center, Cincinnati, Seattle Children's Hospital, Washington University School of Medicine, British Columbia Children's Hospital, The Hospital for Sick Children, St. Justine's Hospital, Temple University

Timeline

N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedMay 19, 2011
Enrollment StartFeb 1, 2012
Primary CompletionJun 1, 2016
TodayJul 2, 2026
Enrollment to primary: 4.3 yearsPosted 15.1 years ago

Interventions

Action-focused problem-solvingbehavioral

* Adherence Support Team (patient, parent, Coach) * standardized education on immunosuppressive medications * identification of adherence barriers * 'Action-Focused Problem-Solving' to address barriers selected as most important by the patient

Electronic pillbox monitoring, dose reminders, and feedbackdevice

* Electronic adherence monitoring with feedback of past 3 months of electronic monitoring data at 3-month intervals * text message, email, or visual cue dose reminders