CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 965 enrolled
Drug / intervention
Lurasidone +1 moredrug
Likely dose
Lurasidone 20 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01358357
NCT01358357Phase 3Completed

A Randomized, Double-blind, Placebo-controlled, Flexible-dose, Parallel-group Study of Lurasidone Adjunctive to Lithium or Divalproex for the Prevention of Recurrence in Subjects With Bipolar I Disorder

Sumitomo Pharma America, Inc.·interventional·Posted May 23, 2011·Updated Sep 7, 2016

In Brief

A Phase 3 clinical trial evaluating Lurasidone and Placebo for Bipolar I Disorder. Completed, enrolled 965 participants across 105 sites in 14 countries.

Detailed Summary

This is a multi-center, randomized, placebo-controlled, flexible-dose, parallel-group study designed to evaluate the efficacy and safety of lurasidone (in combination with lithium or divalproex) for the maintenance treatment of bipolar I disorder in subjects with or without rapid cycling and /or psychotic features.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesArgentina, Australia, Bulgaria, Chile, Croatia, Czechia, France, Hungary, Japan, Poland, Russia, Serbia, Slovakia, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedMay 23, 2011
Enrollment StartJun 1, 2011
Primary CompletionApr 1, 2015
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 15.1 years ago

Interventions

Lurasidonedrug

Lurasidone 20 mg daily (days 1-3), Lurasidone 40 mg daily (days 4-7), Lurasidone 20-80 mg daily (flexible dose) thereafter

Placebodrug

20-80 mg flexible dose