CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 112 enrolled
Drug / intervention
Caffeinated Coffee +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01364207
NCT01364207N/ACompleted

The Effects of Caffeinated Coffee on Intraocular Pressure

Massachusetts Eye and Ear Infirmary·interventional·Posted Jun 2, 2011·Updated Oct 31, 2012

In Brief

A clinical study evaluating Caffeinated Coffee and Decaffeinated Coffee for Primary Open Angle Glaucoma. Completed, enrolled 112 participants across 1 site.

Detailed Summary

High intraocular pressure (IOP) is a known risk factor for developing primary open-angle glaucoma (POAG). There is controversy in the literature regarding the degree to which caffeine influences IOP, with some studies reporting minimal changes in IOP while others report up to 4 mmHg increases. To date there are no double-masked randomized controlled trials that examine acute caffeinated coffee's effects on IOP in patients with or at risk for primary open-angle glaucoma. The investigators aim to better understand the relationship between acute caffeinated coffee (vs decaffeinate coffee) consumption and IOP in a double-masked, crossover randomized controlled clinical trial.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJun 2, 2011
Enrollment StartNov 1, 2010
Primary CompletionAug 1, 2011
Study CompletionJun 1, 2012
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 15.1 years ago

Interventions

Caffeinated Coffeeother

Participants will drink one 8 oz cup in the morning hours. Participants have 15 minutes to drink the coffee but may do so in less time.

Decaffeinated Coffeeother

Participants will drink one 8 oz cup in the morning hours. Participants have 15 minutes to drink the coffee but may do so in less time.