CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 38 enrolled
Drug / intervention
Ketamine +1 moredrug
Likely dose
Ketamine 1.0 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01367119
NCT01367119N/ACompleted
CompareCT.gov

A Randomized Comparison of Ketamine and Methohexital Anesthesia for Electroconvulsive Therapy (ECT) in Depression

Mayo Clinic·interventional·Posted Jun 6, 2011·Updated Aug 8, 2013

In Brief

A clinical study evaluating Ketamine and methohexital for Depression. Completed, enrolled 38 participants across 1 site.

Detailed Summary

Does the use of ketamine as the anesthetic medication in electroconvulsive therapy (ECT) accelerate the antidepressant effect of ECT? The study hypothesis was that depressed subjects receiving ECT with ketamine as the anesthetic agent would demonstrate a faster rate of improvement, defined as lower depression ratings after the second ECT than depressed patients receiving ECT with the usual anesthetic agent.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDepression
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJun 6, 2011
Enrollment StartMay 1, 2011
Primary CompletionMar 1, 2012
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 15.1 years ago

Interventions

Ketaminedrug

Subjects were dosed with approximately 1.0 mg/kg, using ketamine as anesthetic.

methohexitaldrug

Subjects were dosed with approximately 1.0 mg/kg, using methohexital as anesthetic.