At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 16 enrolled
Drug / intervention
Escitalopram +1 moredrug
Likely dose
Escitalopram 10 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Escitalopram (Lexapro) for the Treatment of TBI Depression and Other Comorbid Psychiatric Conditions
In Brief
A Phase 2 clinical trial evaluating Escitalopram and Placebo for TBI and 2 related conditions. Completed, enrolled 16 participants across 1 site.
Detailed Summary
This research is being done to see if a drug called escitalopram (Lexapro) is helpful to people who are suffering from depression after traumatic brain injury (TBI).
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTBI, Major Depression, Other Psychiatric Disorders
CountriesUnited States
CollaboratorsForest Laboratories
Timeline
Phase 2CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartApr 2010
First PostedJun 2011
Primary CompletionDec 2012
Study CompletionMar 2013
TodayJul 2026
First PostedJun 8, 2011
Enrollment StartApr 1, 2010
Primary CompletionDec 1, 2012
Study CompletionMar 1, 2013
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 15.1 years ago
Interventions
Escitalopramdrug
Escitalopram 10 mg or 20 mg daily for 12 weeks by mouth
Placebodrug
Sugar pill placebo