CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 101 enrolled
Drug / intervention
Tranexamic Acid +1 moredrug
Likely dose
Tranexamic Acid 2gfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01370460
NCT01370460Phase 2Completed
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Topical Tranexamic Acid and Acute Blood Loss in Total Knee Arthroplasty

Henry Ford Health System·interventional·Posted Jun 10, 2011·Updated Apr 25, 2023

In Brief

A Phase 2 clinical trial evaluating Tranexamic Acid and Placebo for Acute Blood Loss Anemia and Osteoarthritis, Knee. Completed, enrolled 101 participants across 1 site.

Detailed Summary

This study aims to assess postoperative blood loss and transfusion rates in total knee replacement after one-time administration of topical tranexamic acid.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Blood Loss Anemia, Osteoarthritis, Knee
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJun 10, 2011
Enrollment StartJun 1, 2011
Primary CompletionSep 1, 2012
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 15.1 years ago

Interventions

Tranexamic Aciddrug

Topical tranexamic acid (2g/100mL 0.9% saline)

Placebodrug

100mL 0.9% sterile saline