CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,584 enrolled
Drug / intervention
Isoflurane +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01379664
NCT01379664N/ACompleted

Volatile Anesthetic Choice and Duration of Hospitalization: A Quality Improvement and Cost-control Project

The Cleveland Clinic·interventional·Posted Jun 23, 2011·Updated Apr 10, 2017

In Brief

A clinical study evaluating Isoflurane and Sevoflurane for Duration of Hospitalization. Completed, enrolled 1,584 participants across 1 site.

Detailed Summary

Preliminary retrospective data suggest that the relatively soluble but inexpensive volatile anesthesia isoflurane prolongs the duration of hospitalization compared to the less soluble but more expensive anesthetic sevoflurane. Even a small reduction in the duration of hospitalization would easily compensate for the modest additional cost of sevoflurane. The investigators therefore propose to test the primary hypothesis that duration of hospitalization is longer with isoflurane than sevoflurane. The investigators will also test the secondary hypotheses that: 1) pain scores are greater in patients recovering from isoflurane than sevoflurane anesthesia; and, 2) opioid consumption is greater after isoflurane than sevoflurane anesthesia. All statistical analyses will be adjusted for age, gender, race, baseline risk, 9 and procedure.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedJun 23, 2011
Enrollment StartJul 1, 2011
Primary CompletionApr 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 15.0 years ago

Interventions

Isofluranedrug

Isoflurane is administered to patient during surgery as it would normally be administered by the attending anesthesiologist

Sevofluranedrug

Sevoflurane is administered to patient during surgery as it would normally be administered by the attending anesthesiologist