CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 15 enrolled
Drug / intervention
ridaforolimusdrug
Likely dose
ridaforolimus 10 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01380184
NCT01380184Phase 1Completed

A Study to Assess the Pharmacokinetics of Ridaforolimus in Chinese Patients

Merck Sharp & Dohme LLC·interventional·Posted Jun 27, 2011·Updated Apr 19, 2019

In Brief

A Phase 1 clinical trial evaluating ridaforolimus for Cancer, Advanced. Completed, enrolled 15 participants.

Detailed Summary

Part 1 of the study will assess the pharmacokinetics, safety, and tolerability of ridaforolimus (MK-8669) after administration of single and multiple 40 mg doses in Chinese participants with advanced cancer. Part 2 of the study is optional; participants can continue to receive the study treatment in a weekly regimen of daily oral doses of ridaforolimus 40 mg for five consecutive days followed by two days off-treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 1CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedJun 27, 2011
Enrollment StartJul 5, 2011
Primary CompletionOct 20, 2011
Study CompletionApr 5, 2012
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 15.0 years ago

Interventions

ridaforolimusdrug

4 enteric-coated tablets, each containing 10 mg ridaforolimus, orally (total daily dose: 40 mg)