At a glance
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Impact of Different Fluidic Parameters on Development of Cystoid Macular Edema Following Phacoemulsification
In Brief
A Phase 4 clinical trial evaluating microcoaxial phacoemulsification for Cystoid Macular Edema Following Cataract Surgery. Completed, enrolled 150 participants across 1 site.
Detailed Summary
Understanding and modulating fluid parameters is an important, but often overlooked aspect of phacoemulsification. In a previous study we compared the impact of using high fluid parameters versus low fluidic parameters on real-time IOP measured during phacoemulsification. The investigators found that using high parameters resulted in a higher absolute rise in IOP as well as higher fluctuations in the IOP when compared to low parameters. Clinically these higher fluctuations in IOP would translate in a higher chamber instability. Based on the results of this study, the investigators decided to take it further and study the impact of using high parameters (and thus, higher chamber instability) on macular edema and thickness following surgery, in an otherwise uncomplicated surgery. Higher fluid parameters during phacoemulsification predisposes the eye to increased macular thickness
Study Details
Timeline
Interventions
conventional longitudinal ultrasound