CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 311 enrolled
Drug / intervention
dapagliflozin +1 moredrug
Likely dose
dapagliflozin 10 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01392677
NCT01392677Phase 3Completed

A 24-week, Multicentre, Randomised, Double-Blind, Placebo-Controlled, International Phase III Study With a 28-week Extension Period to Evaluate the Safety and Efficacy of Dapagliflozin 10mg Once Daily in Patients With Type 2 Diabetes Who Have Inadequate Glycaemic Control on a Background Combination of Metformin and Sulfonylurea

AstraZeneca·interventional·Posted Jul 12, 2011·Updated Mar 12, 2014

In Brief

A Phase 3 clinical trial evaluating dapagliflozin and placebo for Type 2 Diabetes Mellitus and 2 related conditions. Completed, enrolled 311 participants across 42 sites in 6 countries.

Detailed Summary

This study intends to compare the efficacy and safety of dapagliflozin versus placebo in patients with type 2 diabetes who have inadequate glycaemic control on a background combination of metformin and sulfonylurea.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, Czechia, Germany, Poland, Slovakia, Spain

Timeline

Phase 3CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedJul 12, 2011
Enrollment StartOct 1, 2011
Primary CompletionJan 1, 2013
Study CompletionAug 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 15.0 years ago

Interventions

dapagliflozindrug

10 mg tablet, oral, once daily, 24- week treatment and 28- week extension period

placebodrug

matching placebo tablet, oral, once daily, 24- week treatment and 28- week extension period