CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 55 enrolled
Drug / intervention
Allergy testsprocedure
Likely dose
Not stated in record
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Search/NCT01407640
NCT01407640N/ACompleted

Diagnosis and Physiopathology of Insulin Allergy (IA)

Assistance Publique - Hôpitaux de Paris·interventional·Posted Aug 2, 2011·Updated Sep 12, 2025

In Brief

A clinical study evaluating Allergy tests for Diabetes Mellitus, Type 1 and 4 related conditions. Completed, enrolled 55 participants across 1 site.

Detailed Summary

Insulin allergy (IA) is still observed even with recombinant human insulin and insulin analogs. Obviously, the usual attitude facing an allergy, i. e. exclusion of the allergen, poses problems in face of IA because insulin is often vital for the patient. IA is thus a complex situation in which a rigorous diagnostic procedure to identify the exact allergen is necessary to propose a therapeutic answer; the purpose of the study is 1/ to validate a diagnostic algorithm for patients presenting with possible allergy. 2/ to investigate immunogenetic profiles of patient with insulin allergy 3/ cellular mechanisms of IA.

Study Details

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedAug 2, 2011
Enrollment StartFeb 6, 2012
Primary CompletionJul 27, 2016
TodayJul 2, 2026
Enrollment to primary: 4.5 yearsPosted 14.9 years ago

Interventions

Allergy testsprocedure

1/ to validate a diagnostic algorithm for patients presenting with possible allergy. 2/ to investigate immunogenetic profiles of patient with insulin allergy 3/ cellular mechanisms of IA