CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 19 enrolled
Drug / intervention
Efavirenz 600mg +2 moredrug
Likely dose
Efavirenz 600mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01410058
NCT01410058N/ACompleted
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Effect of Moringa Oleifera (Moringa, Drumstick/Horseradish Tree) on The Pharmacokinetics of Efavirenz and Nevirapine In-vivo.

University of Zimbabwe·observational·Posted Aug 4, 2011·Updated Apr 2, 2019

In Brief

An observational study evaluating Moringa oleifera, Efavirenz 600mg, and 1 other intervention for HIV. Completed, enrolled 19 participants across 1 site.

Detailed Summary

A study will be conducted by scientists from the University of Zimbabwe to determine if antiretroviral drugs are affected by taking herbs at the same time. This is important because herbal medicines may interact with modern medicine to increase or decrease the amount of medication in the body. The drugs nevirapine and efavirenz will be studied. Both drugs are routinely used as part of combination therapy for treating HIV. In this study it will be determined whether the concentrations of the antiretroviral drugs nevirapine and efavirenz are low, high or are in the desired range when taken together with the herb moringa.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsHIV
CountriesZimbabwe
CollaboratorsState University of New York at Buffalo, Biomedical Research and Training Institute

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedAug 4, 2011
Enrollment StartJan 1, 2013
Primary CompletionSep 1, 2013
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 14.9 years ago

Interventions

Moringa oleiferadietary

leaf powder, 1.85g once daily, hard gelatin capsules

Efavirenz 600mgdrug

Efavirenz 600mg based regimen

Nevirapine 200Mg Oral Tabletdrug

Nevirapine 200mg based regimen