CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 32 enrolled
Drug / intervention
Amoxicillin +2 moredrug
Likely dose
Amoxicillin 250 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01414010
NCT01414010N/ACompleted
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Effects of Mushroom Extract, S Boulardii and Amoxicillin on the Human Microbiome

Beth Israel Deaconess Medical Center·interventional·Posted Aug 11, 2011·Updated Jul 24, 2017

In Brief

A clinical study evaluating Trametes versicolor extract, Saccharomyces boulardii, and 1 other intervention for Human Gut Microbiota. Completed, enrolled 32 participants across 1 site.

Detailed Summary

The purpose of this study is to compare and contrast the effects of a prebiotic (Trametes Versicolor), a probiotic (Saccharomyces boulardii) and an antibiotic (amoxicillin) on the gut microbiota of healthy volunteers. It is expected that treatment will result in the rapid and reproducible alterations in fecal microbiota that will spontaneously reverse in the weeks after treatment is discontinued.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHuman Gut Microbiota
CountriesUnited States
CollaboratorsHong Kong Association for Health Care, Integrated Chinese Medicine Holdings

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedAug 11, 2011
Enrollment StartAug 1, 2011
Primary CompletionFeb 1, 2012
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 14.9 years ago

Interventions

Trametes versicolor extractdietary

1,200 mg, 3 times daily on an empty stomach for 14 days

Saccharomyces boulardiidietary

250 mg, 3 times daily on an empty stomach for 14 days

Amoxicillindrug

250 mg 3 times daily at least 1 hour before meals for 7 days