At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 50 enrolled
Drug / intervention
Radiotherapyradiation
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Phase II Trial of Hippocampal-Avoiding Whole Brain Irradiation With Simultaneous Integrated Boost for Treatment of Brain Metastases
University of Texas Southwestern Medical Center·interventional·Posted Aug 11, 2011·Updated Jan 26, 2021
In Brief
A Phase 2 clinical trial evaluating Radiotherapy for Brain Neoplasms, Adult, Malignant. Completed, enrolled 50 participants across 1 site.
Detailed Summary
The investigators hypothesize that avoidance of the hippocampal region with WBRT (Whole-Brain Radiotherapy ) may delay or reduce the onset, frequency, and/or severity of NCF (neurocognitive function) decline, as measured with clinical neurocognitive tools.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBrain Neoplasms, Adult, Malignant
CountriesUnited States
Collaborators--
Timeline
Phase 2CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedAug 2011
Enrollment StartOct 2011
Primary CompletionDec 2019
TodayJul 2026
First PostedAug 11, 2011
Enrollment StartOct 18, 2011
Primary CompletionDec 16, 2019
TodayJul 2, 2026
Enrollment to primary: 8.2 yearsPosted 14.9 years ago
Interventions
Radiotherapyradiation
Hippocampal-Avoiding Whole Brain Irradiation with Simultaneous Integrated Boost