CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
interscalene nerve block with 0.25% bupivacaine +1 moredrug
Likely dose
interscalene nerve block with 0.25% bupivacaine 20 mlfrom record
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Search/NCT01429584
NCT01429584N/ACompleted

Investigation Into the Effect of 0.25% Bupivacaine for Interscalene Peripheral Nerve Block vs 0.125% Bupivacaine on Pulmonary Function

University of Utah·interventional·Posted Sep 7, 2011·Updated Dec 19, 2013

In Brief

A clinical study evaluating interscalene nerve block with 0.25% bupivacaine and interscalene block with 0.125% bupivacaine for Diaphragm Paralysis. Completed, enrolled 30 participants across 1 site.

Detailed Summary

Peripheral nerve blocks are used to provide post-operative pain relief. Nerve blocks in the neck, in the interscalene area, provide pain relief after shoulder surgery but can cause temporary weakness or paralysis of the diaphragm. The investigators hypothesized that a lower concentration of bupivacaine would cause less weakness of the diaphragm but still provide good pain relief. Lung function and pain control was studied after interscalene peripheral nerve block with 20 milliliters of 0.25% bupivacaine or 0.125% bupivacaine.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 7, 2011
Enrollment StartMay 1, 2008
Primary CompletionFeb 1, 2010
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 14.8 years ago

Interventions

interscalene nerve block with 0.25% bupivacainedrug

interscalene nerve block performed with 20 ml of 0.25% bupivacaine

interscalene block with 0.125% bupivacainedrug

interscalene block with 20 ml of 0.125% bupivacaine