CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 200 enrolled
Drug / intervention
strategies to reverse decrease in rSO2procedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01432184
NCT01432184N/ACompleted
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Perioperative Interventions to Optimize Cerebral Oxygen Saturation (rSO2) in High-risk Patients Undergoing Cardiac Surgery Should Have a Beneficial Systemic Effect for Enhancing Global Tissue Perfusion and Improve Outcomes.

Montreal Heart Institute·interventional·Posted Sep 12, 2011·Updated Oct 20, 2015

In Brief

A clinical study evaluating strategies to reverse decrease in rSO2 for Cerebral Hypoxia. Completed, enrolled 200 participants across 1 site.

Detailed Summary

Using the brain and the heart as index organs, perioperative interventions to optimize cerebral oxygen saturation and cardiac contractility in high-risk patients undergoing cardiac surgery should have a beneficial systemic effect for enhancing global tissue perfusion and improve outcomes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCerebral Hypoxia
CountriesCanada
CollaboratorsUniversité de Montréal

Timeline

N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedSep 12, 2011
Enrollment StartJul 1, 2010
Primary CompletionJul 1, 2011
Study CompletionOct 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 14.8 years ago

Interventions

strategies to reverse decrease in rSO2procedure

an alarm threshold at a value of 90% of the resting baseline cerebral saturation value (baseline - 10%) will be established. To minimize the probability of patients reaching significant decreases rSO2 values, interventions to improve cerebral oxygenation will be initiated according to the strategies described in the algorithm. The success and failure of these interventions will be noted. As in the Control group, the screen will remain blinded in the ICU and the intensivist will not see the values.