CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 49 enrolled
Drug / intervention
PF-04950615 (RN316) +3 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01435382
NCT01435382Phase 1Completed

A Phase 1, Open-label, Randomized, Single Dose, Parallel Group Study To Assess The Pharmacokinetics And Pharmacodynamics Of Pf-04950615 Following Subcutaneous And Intravenous Doses In Adult Subjects With Hypercholesterolemia

Pfizer·interventional·Posted Sep 16, 2011·Updated Jul 23, 2018

In Brief

A Phase 1 clinical trial evaluating PF-04950615 (RN316) for Hypercholesterolemia and 4 related conditions. Completed, enrolled 49 participants across 7 sites.

Detailed Summary

This Phase 1 study has been designed to evaluate the absolute bioavailability of PF-04950615 (RN316) in subjects with hypercholesterolemia who are not currently on lipid-lowering therapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedSep 16, 2011
Enrollment StartOct 1, 2011
Primary CompletionFeb 1, 2012
Study CompletionApr 1, 2012
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 14.8 years ago

Interventions

PF-04950615 (RN316)biological

Dose A - single-dose intravenous infusion

PF-04950615 (RN316)biological

Dose B - single-dose subcutaneous injection

PF-04950615 (RN316)biological

Dose C - single-dose subcutaneous injection

PF-04950615 (RN316)biological

Dose D - single-dose subcutaneous injection