At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 400 enrolled
Drug / intervention
Lorazepam +1 moredrug
Likely dose
Lorazepam 1mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Resistance Under the Microscope; a Randomized Placebo Controlled Parallel Group Design
In Brief
A Phase 4 clinical trial evaluating Lorazepam and NaCl 0.9% (Sodium Chloride) for Anxiety. Completed, enrolled 400 participants across 1 site.
Detailed Summary
The purpose of this study is to determine whether lorazepam, which is used to lower preoperative anxiety, also improves postoperative recovery. This study data will also be used for further research aiming to identify vulnerable patients in the day-case surgery setting.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnxiety
CountriesNetherlands
Collaborators--
Timeline
Phase 4CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
Enrollment StartOct 2010
Primary CompletionSep 2011
First PostedSep 2011
TodayJul 2026
First PostedSep 28, 2011
Enrollment StartOct 1, 2010
Primary CompletionSep 1, 2011
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 14.8 years ago
Interventions
Lorazepamdrug
Once 1mg \<75kg body weight, 1.5mg 75kg and \>75kg body weight, IV, before surgery
NaCl 0.9% (Sodium Chloride)drug
Once 1ml \<75kg body weight, 1.5ml 75kg or \>75kg body weight, IV, before surgery