CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 353 enrolled
Drug / intervention
Technosphere® Insulin +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01451398
NCT01451398Phase 3Completed

A Phase 3, Multicenter, Double-blind, Placebo-controlled, Randomized, Clinical Trial Evaluating the Efficacy and Safety of Prandial Technosphere® Insulin Inhalation Powder Versus Technosphere Inhalation Powder in Insulin Naïve Subjects With Type 2 Diabetes Mellitus Poorly Controlled With Oral Antidiabetic Agents Over a 24 Week Treatment Period

Mannkind Corporation·interventional·Posted Oct 13, 2011·Updated Oct 17, 2014

In Brief

A Phase 3 clinical trial evaluating Technosphere® Insulin and Technosphere Powder for Type 2 Diabetes. Completed, enrolled 353 participants across 76 sites in 4 countries.

Detailed Summary

Insulin-naive subjects with Type 2 Diabetes Mellitus who are sub-optimally controlled on either maximum tolerated dose of metformin or maximum tolerated dose of metformin plus one or two other oral anti-diabetic medications will have either Prandial Technosphere® Insulin or Technosphere Powder (placebo) added to their oral antidiabetic drugs.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType 2 Diabetes
CountriesBrazil, Russia, Ukraine, United States
Collaborators--

Timeline

Phase 3CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedOct 13, 2011
Enrollment StartNov 1, 2011
Primary CompletionJun 1, 2013
Study CompletionJul 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 14.7 years ago

Interventions

Technosphere® Insulindrug

Technosphere® Insulin Inhalation Powder

Technosphere Powderdrug

Placebo Comparator