CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 103 enrolled
Drug / intervention
Radiation Therapy +1 moreradiation
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01459497
NCT01459497Phase 3Completed
CompareCT.gov

Phase III Randomized Study of Standard Versus Accelerated Hypofractionated Image-Guided Radiation Therapy (IGRT) in Patients With Stage II-III Non-Small Cell Lung Cancer and Poor Performance Status

University of Texas Southwestern Medical Center·interventional·Posted Oct 25, 2011·Updated Jan 17, 2024

In Brief

A Phase 3 clinical trial evaluating Radiation Therapy and Conventional radiation for Non-small Cell Lung Cancer. Completed, enrolled 103 participants across 7 sites.

Detailed Summary

The study is designed to determine whether an accelerated course of hypofractionated radiation therapy with daily image guidance and motion assessment/control will allow more effective treatment of poor performance status patients with stage II-III NSCLC, who would benefit from local therapy compared to standard radiation therapy (60 Gy in 2 Gy per fraction).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNon-small Cell Lung Cancer
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedOct 25, 2011
Enrollment StartOct 1, 2012
Primary CompletionJul 11, 2019
Study CompletionOct 19, 2023
TodayJul 2, 2026
Enrollment to primary: 6.8 yearsPosted 14.7 years ago

Interventions

Radiation Therapyradiation

Image-Guided Radiation Therapy (IGRT)60 Gy in 15 fractions in 3 weeks

Conventional radiationradiation

Conventional radiation 60-66 Gy in 30-33 fractions in 6-7 weeks