At a glance
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Study to Identify the Genetic Variations Associated With Phantom Limb Pain
In Brief
An observational study evaluating Blood Draw for Phantom Limb. Completed, enrolled 726 participants across 1 site.
Detailed Summary
The purpose of this study is to determine if there is a genetic component to phantom limb pain. DNA will be analyzed for single nucleotide polymorphisms (SNPs) between the control and phantom limb pain group. Total RNA will also be isolated and profiled to asses the degree to which our gene(s) of interest are expressed in the presence or absence of phantom limb pain. Some proteins, such as inflammatory antibodies or the neurotrophin brain-derived neurotrophic factor (BDNF), will also be assessed for their association(s) with phantom limb pain.
Study Details
Timeline
Interventions
Single blood draw of 30 ml