CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 2,443 enrolled
Drug / intervention
Aclidinium Bromide/Formoterol Fumarate +4 moredrug
Likely dose
Aclidinium Bromide/Formoterol Fumarate 6 μgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01462942
NCT01462942Phase 3Completed

Efficacy and Safety of Aclidinium Bromide/Formoterol Fumarate Fixed-dose Combinations Compared With Individual Components and Placebo When Administered to Patients With Stable Chronic Obstructive Pulmonary Disease.

AstraZeneca·interventional·Posted Nov 1, 2011·Updated Feb 15, 2017

In Brief

A Phase 3 clinical trial evaluating Aclidinium Bromide/Formoterol Fumarate, Aclidinium Bromide, and 2 other interventions for Chronic Obstructive Pulmonary Disease (COPD). Completed, enrolled 2,443 participants across 197 sites in 22 countries.

Detailed Summary

The objective is to provide data supporting the use of LAS40464 as an efficacious and safe maintenance bronchodilator treatment of patients with Chronic Obstructive Pulmonary Disease (COPD).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustria, Belgium, Bulgaria, Croatia, Czechia, Denmark, Finland, France, Germany, Hungary, Italy, Netherlands, Poland, Romania, Russia, Slovakia, South Africa, South Korea, Spain, Sweden, Ukraine, United Kingdom
Collaborators--

Timeline

Phase 3CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedNov 1, 2011
Enrollment StartOct 1, 2011
Primary CompletionJan 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 14.7 years ago

Interventions

Aclidinium Bromide/Formoterol Fumaratedrug

Inhaled Aclidinium/formoterol Fixed Dose Combination (FDC) low dose (400/6 μg), twice per day

Aclidinium Bromide/Formoterol Fumaratedrug

Inhaled Aclidinium/formoterol FDC high dose (400/12 μg), twice per day

Aclidinium Bromidedrug

Inhaled Aclidinium 400 μg, twice per day

Placebodrug

Inhaled dose-matched placebo, twice per day

Formoterol Fumaratedrug

Inhaled Formoterol 12 μg, twice per day