CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 614 enrolled
Drug / intervention
tofacitinib +1 moredrug
Likely dose
tofacitinib 10 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01465763
NCT01465763Phase 3Completed

A Multicentre, Randomized, Double-blind, Placebo-controlled, Parallel-group Study Of Oral Cp-690,550 As An Induction Therapy In Subjects With Moderate To Severe Ulcerative Colitis

Pfizer·interventional·Posted Nov 7, 2011·Updated Jun 7, 2016

In Brief

A Phase 3 clinical trial evaluating tofacitinib and Placebo for Ulcerative Colitis. Completed, enrolled 614 participants across 178 sites in 28 countries.

Detailed Summary

This study is designed to evaluate the efficacy and safety of tofacitinib (CP-690,550) in patients with moderate to severe ulcerative colitis who have failed or be intolerant to one of following treatments for ulcerative colitis: oral steroids, azathiopurine/6-mercaptopurine, or anti-TNF-alpha therapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Austria, Belgium, Canada, Colombia, Croatia, Czechia, Denmark, Estonia, France, Germany, Hungary, Israel, Italy, Japan, Latvia, Netherlands, New Zealand, Poland, Romania, Russia, Serbia, Slovakia, South Africa, Spain, Ukraine, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedNov 7, 2011
Enrollment StartApr 1, 2012
Primary CompletionMay 1, 2015
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 14.7 years ago

Interventions

tofacitinibdrug

10 mg oral BID

Placebodrug

Plabebo oral BID