CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled
Drug / intervention
Hypercapnia during thoracoscopy +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01467245
NCT01467245N/ACompleted
CompareCT.gov

Hypercapnia During Thoracoscopy or Open Surgery for Repair of Oesophageal Atresia With Tracheo-oesophageal Fistula or Congenital Diaphragmatic Hernia in Neonates: Pilot Randomised Controlled Trial

Great Ormond Street Hospital for Children NHS Foundation Trust·interventional·Posted Nov 8, 2011·Updated Mar 2, 2022

In Brief

A clinical study evaluating Hypercapnia during thoracoscopy and Open surgery for Esophageal Atresia With Tracheo-esophageal Fistula and Congenital Diaphragmatic Hernia. Completed, enrolled 20 participants across 1 site.

Detailed Summary

This is a pilot randomised controlled trial comparing open versus thoracoscopic surgery for repair of oesophageal atresia with tracheo-oesophageal fistula or congenital diaphragmatic hernia in neonates. Thoracoscopic surgery involves insufflation of carbon dioxide into the thoracic cavity and may therefore cause hypercapnia and acidosis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsEsophageal Atresia With Tracheo-esophageal Fistula, Congenital Diaphragmatic Hernia
CountriesUnited Kingdom
Collaborators--

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedNov 8, 2011
Enrollment StartAug 1, 2009
Primary CompletionFeb 1, 2011
Study CompletionAug 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 14.7 years ago

Interventions

Hypercapnia during thoracoscopyprocedure

keyhole surgery through the chest for repair of oesophageal atresia with tracheo-oesophageal fistula or congenital diaphragmatic hernia in neonates

Open surgeryprocedure

open surgery for repair of oesophageal atresia with tracheo-oesophageal fistula or congenital diaphragmatic hernia in neonates