CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 18 enrolled
Drug / intervention
docetaxel +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01468532
NCT01468532Phase 2Completed

Phase I/II Trial to Establish the Safety and Preliminary Efficacy of the Combination of Docetaxel, Prednisone, and SOM 230 (Pasireotide) in Metastatic Castrate Resistant Prostate Cancer (CRPC).

Barbara Ann Karmanos Cancer Institute·interventional·Posted Nov 9, 2011·Updated Mar 25, 2021

In Brief

A Phase 2 clinical trial evaluating docetaxel, pasireotide, and 1 other intervention for Adenocarcinoma of the Prostate and 3 related conditions. Completed, enrolled 18 participants across 1 site.

Detailed Summary

This phase I/II trial studies the side effects and best dose of pasireotide and to see how well it works when given together with docetaxel and prednisone in treating patients with metastatic hormone-resistant prostate cancer. Drugs used in chemotherapy, such as docetaxel and prednisone, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Pasireotide may inhibit the secretion of hormones. Giving pasireotide together with docetaxel and prednisone may kill more tumor cells.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedNov 9, 2011
Enrollment StartOct 1, 2011
Primary CompletionJul 20, 2017
TodayJul 2, 2026
Enrollment to primary: 5.8 yearsPosted 14.6 years ago

Interventions

docetaxeldrug

Given IV

pasireotidedrug

Given IM

prednisonedrug

Given PO