CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,369 enrolled
Drug / intervention
LY2605541 +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01468987
NCT01468987Phase 3Completed

The Impact of LY2605541 Versus Insulin Glargine for Patients With Type 2 Diabetes Mellitus Advanced to Multiple Injection Bolus Insulin With Insulin Lispro: a Double-Blind, Randomized, 26-week Study - The IMAGINE 4 Study

Eli Lilly and Company·interventional·Posted Nov 10, 2011·Updated Apr 17, 2018

In Brief

A Phase 3 clinical trial evaluating LY2605541, Insulin Glargine, and 1 other intervention for Diabetes Mellitus, Type 2. Completed, enrolled 1,369 participants across 156 sites in 25 countries.

Detailed Summary

The purpose of this study is: * To compare blood glucose (blood sugar) control on LY2605541 with insulin glargine after 26 weeks of treatment. * To compare the rate of night time hypoglycemia (low blood glucose) on LY2605541 with insulin glargine during 26 weeks of treatment. * To compare the number of participants on LY2605541 reaching blood glucose targets without hypoglycemia episodes at night to those taking insulin glargine after 26 weeks of treatment. * To compare the rate of hypoglycemia over a 24-hour period on LY2605541 with insulin glargine during 26 weeks of treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Austria, Brazil, Croatia, Czechia, Denmark, Germany, Greece, Hungary, Israel, Italy, Japan, Lithuania, Mexico, Netherlands, Poland, Puerto Rico, Romania, Russia, Slovakia, Spain, Taiwan, Turkey (Türkiye), United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedNov 10, 2011
Enrollment StartDec 1, 2011
Primary CompletionAug 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 14.6 years ago

Interventions

LY2605541drug

Insulin Glarginedrug

Insulin Lisprodrug