CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 161 enrolled
Drug / intervention
Clinical evaluation +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01476644
NCT01476644N/ACompleted
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A Prospective, Longitudinal, Observational Cohort Study Examining How Glaucoma Affects Quality of Life and Visual Function Over a 4-Year Period

Wills Eye·interventional·Posted Nov 22, 2011·Updated Nov 15, 2019

In Brief

A clinical study evaluating Clinical evaluation, Performance based measures, and 1 other intervention for Glaucoma and Quality of Life. Completed, enrolled 161 participants across 1 site.

Detailed Summary

Hypothesis 1: Self-reported health-related quality of life decreases as vision impairment worsens in subjects with glaucoma. Hypothesis 2: Changes in health-related quality of life are associated with changes in clinical measures of vision and performance-based measures of visual function.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGlaucoma, Quality of Life
CountriesUnited States
CollaboratorsMerck Sharp & Dohme LLC

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedNov 22, 2011
Enrollment StartOct 1, 2011
Primary CompletionJul 1, 2016
Study CompletionJun 1, 2017
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 14.6 years ago

Interventions

Clinical evaluationother

Biomicroscopy (look at front of eye), ophthalmoscopy (look at back of eye), visual acuity, visual fields, intraocular pressure, spectral domain optical coherence tomography, Pelli-Robson and the Spaeth-Richman Contrast Sensitivity tests

Performance based measuresother

Compressed Assessment of Ability Related to Vision (CAARV) items include: 1) computerized motion detection; 2) recognizing facial expressions; 3) reading street signs; and 4) finding objects in a room

Subjective measures of vision-related quality of lifeother

National Eye Institute Visual Functioning Questionnaire 25 (NEI-VFQ-25) includes a series of questions pertaining to vision or feelings about a vision condition and the Modified Glaucoma Symptom Scale (MGSS) includes a series of questions pertaining to eye comfort.