CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 8 enrolled
Drug / intervention
ABT-SLV187 +4 moredrug
Likely dose
Oral Levodopa/Carbidopa 100 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01479127
NCT01479127Phase 2Completed
CompareCT.gov

An Open-Label, Single-Arm, Baseline-Controlled, Multicenter Study to Explore the Safety, Tolerability, Pharmacokinetics, and Efficacy of ABT-SLV187 in Subjects With Advanced Parkinson's Disease

AbbVie (prior sponsor, Abbott)·interventional·Posted Nov 24, 2011·Updated Apr 21, 2016

In Brief

A Phase 2 clinical trial evaluating ABT-SLV187, Oral Levodopa/Carbidopa, and 3 other interventions for Advanced Parkinson's Disease. Completed, enrolled 8 participants.

Detailed Summary

To explore the safety, tolerability, pharmacokinetics and efficacy of ABT-SLV187 in advanced Parkinson's disease (PD) patients with severe motor complications. The complications of medical devices for the naso-jejunum (NJ) infusion system of ABT-SLV187 will also be investigated.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAdvanced Parkinson's Disease
Countries--
CollaboratorsAbbott Japan Co.,Ltd

Timeline

Phase 2CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedNov 24, 2011
Enrollment StartOct 1, 2011
Primary CompletionJul 1, 2012
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 14.6 years ago

Interventions

ABT-SLV187drug

Oral Levodopa/Carbidopadrug

Tablet; contains 100 mg levodopa and 10 mg carbidopa

Infusion Pump: CADD-Legacy® 1400 Pumpdevice

General infusion pump, manufactured by Smiths Medical (US)

NJ-Tube: Silicon ED Tubedevice

Device used to deliver nutrition/drug to stomach/intestine or to aspirate stomach fluid, manufactured by Create Medic Co., Ltd. (Japan)

Adaptor: Hakko Adaptordevice

Accessory set for fluid infusion set, consisting of caps, connectors and adapters, etc, manufactured by Hakko Medical (Japan)