CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 154 enrolled
Drug / intervention
Sugammadex +2 moredrug
Likely dose
Sugammadex 4 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01479764
NCT01479764Phase 3Completed

Effect of Sugammadex Compared With Usual Care for Reversal of Neuromuscular Blockade Induced by Rocuronium on Incidence of Residual Blockade at PACU Entry

Merck Sharp & Dohme LLC·interventional·Posted Nov 24, 2011·Updated Jun 6, 2017

In Brief

A Phase 3 clinical trial evaluating Sugammadex, Neostigmine, and 1 other intervention for Surgical Procedures, Elective. Completed, enrolled 154 participants.

Detailed Summary

This study will compare the incidence of residual neuromuscular blockade in participants who undergo reversal of neuromuscular blockade with sugammadex compared to those who undergo reversal of neuromuscular blockade with usual care (neostigmine/glycopyrrolate).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedNov 24, 2011
Enrollment StartDec 2, 2011
Primary CompletionOct 26, 2012
Study CompletionNov 5, 2012
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 14.6 years ago

Interventions

Sugammadexdrug

sugammadex, intravenous (IV) bolus, 2 or 4 mg/kg depending on level of neuromuscular recovery

Neostigminedrug

neostigmine, per usual practice

Glycopyrrolatedrug

glycopyrrolate per usual practice