CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 283 enrolled
Drug / intervention
Xeomin®biological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01486264
NCT01486264Phase 4Completed

An Open-Label, Non-Inferiority Study Evaluating the Efficacy and Safety of Two Injection Schedules of Xeomin® (incobotulinumtoxinA) [Short Flex Versus Long Flex] in Subjects With Cervical Dystonia With < 10 Weeks of Benefit From OnabotulinumtoxinA Treatment

Merz Pharmaceuticals GmbH·interventional·Posted Dec 6, 2011·Updated Oct 27, 2022

In Brief

A Phase 4 clinical trial evaluating Xeomin® for Cervical Dystonia. Completed, enrolled 283 participants across 43 sites.

Detailed Summary

This study will compare Xeomin®, a botulinum toxin medication, in shorter treatment intervals (Short Flex dosing) to the standard interval dosing (Long Flex dosing) to determine if the response to treatment is comparable in both how it works and any side effects. Xeomin® is approved by the United States Food and Drug Administration (FDA) for the treatment of cervical dystonia (CD). The use of Xeomin® is investigational in regards to shorter treatment intervals. An investigational use is one that is not approved by the FDA.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 4CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedDec 6, 2011
Enrollment StartJan 20, 2012
Primary CompletionMar 29, 2016
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 14.6 years ago

Interventions

Xeomin®biological

Xeomin is botulinum toxin type A produced from fermentation of Hall strain Clostridium botulinum serotype A