CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 24 enrolled
Drug / intervention
Insertion of nitroglycerin ointment +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01490073
NCT01490073N/ACompleted

The Effect of Nitroglycerin on the IUD Insertion Experience in Nulliparous Women: a Pilot Study

Oregon Health and Science University·interventional·Posted Dec 12, 2011·Updated Apr 26, 2019

In Brief

A clinical study evaluating Insertion of nitroglycerin ointment and Insertion of placebo ointment for Contraception and Pain. Completed, enrolled 24 participants across 2 sites.

Detailed Summary

Increasing ease of access of long-acting birth control methods, like intrauterine devices (IUDs), is an important way to reduce the risk of unintended pregnancy. Unfortunately, fear of IUD insertion in women who have not had children is common among health care providers and women alike, and this limits IUD use. To increase acceptance of this highly effective birth control method, there is a need to explore new, low cost, and easily applied methods to improve the insertion experience. This is a pilot study to evaluate the effectiveness and acceptability of nitroglycerin ointment applied vaginally to improve the IUD insertion experience for both patient and provider. The investigators hypothesis is that nitroglycerin ointment will decrease the pain associated with IUD insertion.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsContraception, Pain
CountriesUnited States

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedDec 12, 2011
Enrollment StartMar 1, 2012
Primary CompletionNov 1, 2012
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 14.6 years ago

Interventions

Insertion of nitroglycerin ointmentdrug

Nitroglycerin ointment inserted into the vagina 30-45 minutes prior to IUD insertion

Insertion of placebo ointmentdrug

Placebo ointment inserted into the vagina 30-45 minutes prior to IUD insertion