CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 165 enrolled
Drug / intervention
Placebo matching BMS-945429 +3 morebiological
Likely dose
Placebo matching BMS-945429 0 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01490450
NCT01490450Phase 2Completed

A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Dose Ranging, Multi-Center Study to Evaluate the Efficacy and Safety of BMS-945429 Subcutaneous Injection in Adults With Active Psoriatic Arthritis

CSL Behring·interventional·Posted Dec 13, 2011·Updated Nov 5, 2021

In Brief

A Phase 2 clinical trial evaluating Placebo matching BMS-945429 and BMS-945429 for Arthritis, Psoriatic. Completed, enrolled 165 participants across 49 sites in 13 countries.

Detailed Summary

The purpose of this study is to characterize the safety, efficacy and dose response of BMS-945429 in subjects with active Psoriatic Arthritis and an inadequate response to Nonsteroidal anti-inflammatory drugs (NSAIDs) and non-biologic Disease modifying anti-rheumatic drugs (DMARDs).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesArgentina, Australia, Canada, Czechia, Germany, Hungary, Italy, Mexico, Poland, Russia, South Africa, Spain, United States
Collaborators--

Timeline

Phase 2CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedDec 13, 2011
Enrollment StartDec 1, 2011
Primary CompletionJun 1, 2013
Study CompletionJun 1, 2015
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 14.6 years ago

Interventions

Placebo matching BMS-945429biological

Injection, Subcutaneous, 0 mg, every 4 weeks, Short term:24 weeks, Long term: After 24 Wk, selected dose, open-label

BMS-945429biological

Injection, Subcutaneous, 25 mg, every 4 weeks, Short term:24 weeks, Long term: After 24 Wk, selected dose, open-label

BMS-945429biological

Injection, Subcutaneous, 100 mg, every 4 weeks, Short term:24 weeks, Long term: After 24 Wk, selected dose, open-label

BMS-945429biological

Injection, Subcutaneous, 200 mg, every 4 weeks, Short term:24 weeks, Long term: After 24 Wk, selected dose, open-label