CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,236 enrolled
Drug / intervention
Potentially Reduced Exposure Product (PREP): a smokeless, spit-free tobacco productdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01509586
NCT01509586N/ACompleted

A Test of Short and Long Term Naturalistic Outcomes of Smokers Who Sample Smokeless Tobacco

Medical University of South Carolina·interventional·Posted Jan 13, 2012·Updated Jul 12, 2023

In Brief

A clinical study evaluating Potentially Reduced Exposure Product (PREP): a smokeless, spit-free tobacco product for Smoking and Smoking Cessation. Completed, enrolled 1,236 participants across 1 site.

Detailed Summary

This nationwide telephone and mail- based research study will recruit 1,400 cigarette smokers who are not motivated to quit to test the effects of a marketed oral, non-combustible smokeless tobacco product on cigarette smoking behaviors. It will also track the participants' usage patterns of the smokeless tobacco product. Half of the participants will receive a new, potentially safer tobacco product during the first six weeks of the study, and half will not. During this six-week period, each participant will complete three brief phone interviews. After this first six week period, participants will complete 6 other brief follow-up interviews, where they will answer questionnaires about their smoking habits.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedJan 13, 2012
Enrollment StartNov 1, 2011
Primary CompletionMar 1, 2016
TodayJul 2, 2026
Enrollment to primary: 4.3 yearsPosted 14.5 years ago

Interventions

Potentially Reduced Exposure Product (PREP): a smokeless, spit-free tobacco productdrug

The PREP Group will be given a sample supply of a PREP product that is already on the market. It is unclear if it is safer than cigarettes, and that is why it is classified as a Potentially Reduced Exposure Product. It provides both nicotine and tobacco in the form of a pouch that can be thrown away after used. Unlike chewing tobacco, there is no need for spitting with this product. There are multiple flavors and participants will have his/her choice of preferred flavor. This group will be asked to sample the product and use it in several ways, but whether a participant uses the product or not is up him/her.