At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effects of Prophylactic Subcutaneous Fentanyl on Exercise-Induced Breakthrough Dyspnea in Cancer Patients: A Preliminary Double-Blind, Randomized Controlled Trial
In Brief
A Phase 2 clinical trial evaluating Fentanyl, Placebo, and 2 other interventions for Advanced Cancers and Dyspnea. Completed, enrolled 26 participants across 1 site.
Detailed Summary
The goal of this clinical research study is to learn if fentanyl given under the skin can reduce shortness of breath in cancer patients. Researchers also want to learn if it can help to improve your physical function. In this study, fentanyl will be compared to a placebo. Fentanyl is commonly used for treatment of cancer pain. It is believed to help patients with their shortness of breath as well. A placebo is not a drug. It looks like the study drug but is not designed to treat any disease or illness. It is designed to be compared with a study drug to learn if the study drug has any real effect.
Study Details
Timeline
Interventions
Fentanyl SQ dose equivalent to 15-25% of the morphine equivalent daily dose (MEDD) 15 minutes before 6 minute walk test.
Normal saline 0.9% preservative free SQ 15 minutes before walk test.
6 minute walk test at baseline and 15 minutes after Fentanyl or Placebo.
Questionnaires completed at baseline (two) and after study visit (one) taking about 5 ot 10 minutes to complete.