At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 121 enrolled
Drug / intervention
botulinum toxin Type A +1 morebiological
Likely dose
botulinum toxin Type A 2 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Safety and Efficacy Study of Botulinum Toxin Type A as Treatment for Osteoarthritis Knee Pain
In Brief
A Phase 2 clinical trial evaluating botulinum toxin Type A and Normal Saline for Osteoarthritis. Completed, enrolled 121 participants across 1 site.
Detailed Summary
This study will evaluate the efficacy and safety of a single intra-articular (IA) injection of botulinum toxin Type A compared with placebo as treatment for osteoarthritis (OA) knee pain.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthritis
CountriesDenmark
Collaborators--
Timeline
Phase 2CompletedFinished
201220132014201520162017201820192020202120222023202420252026
Enrollment StartJan 2012
First PostedJan 2012
Primary CompletionJan 2013
TodayJul 2026
First PostedJan 25, 2012
Enrollment StartJan 1, 2012
Primary CompletionJan 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 14.4 years ago
Interventions
botulinum toxin Type Abiological
A single 200U (2 mL) dose of botulinum toxin Type A injected into the intra-articular space of the study knee on Day 1.
Normal Salinedrug
A single 2 mL dose of Normal Saline (placebo) injected into the intra-articular space of the study knee on Day 1.