At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomised Controlled Trial to Compare Unfractionated Heparin Versus Bivalirudin in the Treatment of Patients With a Clinical Diagnosis of ST-Segment Elevation Myocardial Infarction Events - For Planned Management With Primary PCI
In Brief
A Phase 4 clinical trial evaluating unfractionated heparin and Bivalirudin for Acute ST Elevation Myocardial Infarction. Completed, enrolled 1,829 participants across 1 site.
Detailed Summary
The purpose of this study is to compare unfractionated heparin (UFH) and bivalirudin in the performance and subsequent outcomes of Primary percutaneous coronary intervention. This will be a pragmatic trial. Interventional procedures will be performed to reflect current and evolving standards, including predominant radial access. All patients will be treated with routine oral anti-platelet therapy pre-procedure. GP IIb/IIIa inhibitors will be reserved for 'bail out' treatment only.
Study Details
Timeline
Interventions
70 units/kg body weight intravenous
intravenous bolus of 0.75 mg/kg followed by infusion of 1.75 mg/kg per hour