CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 300 target
Drug / intervention
Ibuprofen +1 moredrug
Likely dose
Ibuprofen 400mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01522326
NCT01522326N/ACompleted
CompareCT.gov

Acute Mountain Sickness Treatment: A Double-blind Comparison of Metoclopramide vs. Ibuprofen

Massachusetts General Hospital·interventional·Posted Jan 31, 2012·Updated Sep 2, 2020

In Brief

A clinical study evaluating Ibuprofen and Metoclopramide for Acute Mountain Sickness and High Altitude Headache. Completed, enrolled 300 participants across 1 site.

Detailed Summary

The objective of this study is to determine the efficacy of metoclopramide in relieving the symptoms of Acute Mountain Sickness (AMS). It is our hypothesis that the combined antiemetic and analgesic effects of metoclopramide (which has been study-proven to be effective in relieving symptoms of migraine headache) will prove to be more efficacious in relieving symptoms of acute mountain sickness than the standard, previously-studied analgesic medication, ibuprofen.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Mountain Sickness, High Altitude Headache
CountriesNepal
Collaborators--

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedJan 31, 2012
Enrollment StartMar 1, 2012
Primary CompletionMar 1, 2017
Study CompletionMar 30, 2017
TodayJul 2, 2026
Enrollment to primary: 5 yearsPosted 14.4 years ago

Interventions

Ibuprofendrug

Ibuprofen 400mg tablet. Take one dose by mouth.

Metoclopramidedrug

Metoclopramide 10mg tablet. Take one tablet by mouth.