At a glance
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Phase II Trial of Neoadjuvant Chemotherapy With Carboplatin and NAB-Paclitaxel in Patients With Locally Advanced and Inflammatory Triple Negative Breast Cancer
In Brief
A Phase 2 clinical trial evaluating carboplatin, paclitaxel albumin-stabilized nanoparticle formulation, and 1 other intervention for Inflammatory Breast Cancer and 9 related conditions. Active but no longer recruiting, targeting 67 participants across 2 sites.
Detailed Summary
This phase II trial studies how well carboplatin and nab-paclitaxel before surgery work in treating patients with triple negative breast cancer that is inflammatory or has spread from where it started to nearby tissue or lymph nodes. Drugs used in chemotherapy, such as carboplatin and nab-paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed.
Study Details
Timeline
Interventions
Given IV
Given IV
Correlative studies