CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 355 enrolled
Drug / intervention
100 IR house dust mites allergen extract tablet +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01527188
NCT01527188Phase 2Completed

A Randomized, Double-blind, Placebo-controlled, Dose Ranging Phase II Study to Assess the Efficacy and Safety of 100IR, 300IR and 500IR Sublingual Tablets of House Dust Mite Allergen for the Treatment of Allergic Rhinitis in an Environmental Exposure Chamber Model

Stallergenes Greer·interventional·Posted Feb 6, 2012·Updated Feb 4, 2025

In Brief

A Phase 2 clinical trial evaluating 100 IR house dust mites allergen extract tablet, 300 IR house dust mites allergen extract tablet, and 2 other interventions for Allergic Rhinitis Due to House Dust Mite. Completed, enrolled 355 participants across 1 site.

Detailed Summary

The purpose of this study is to assess the effect of 3 doses of sublingual house dust mite (HDM) tablets versus placebo in the change from baseline of rhinitis total symptom score during the allergen chamber challenge before and after 6 months of treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada
Collaborators--

Timeline

Phase 2CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedFeb 6, 2012
Enrollment StartDec 8, 2010
Primary CompletionMar 1, 2012
Study CompletionSep 19, 2012
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 14.4 years ago

Interventions

100 IR house dust mites allergen extract tabletdrug

One sublingual tablet daily during 6 months

300 IR house dust mites allergen extract tabletdrug

One sublingual tablet daily during 6 months

500 IR house dust mites allergen extract tabletdrug

One sublingual tablet daily during 6 months

Placebo tabletdrug

One sublingual tablet daily during 6 months