CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 67 enrolled
Drug / intervention
Inspired oxygen fraction / end tidal carbon dioxideother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01535274
NCT01535274N/ACompleted
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The Influence of Basic Ventilation Strategies and Anesthetic Techniques on Cerebral Oxygenation in the Beach Chair Position

University of Michigan·interventional·Posted Feb 17, 2012·Updated Apr 6, 2022

In Brief

A clinical study evaluating Inspired oxygen fraction / end tidal carbon dioxide for Stroke. Completed, enrolled 67 participants across 1 site.

Detailed Summary

The seated or "beach chair" position during surgery and general anesthesia decreases brain oxygen levels and can result in stroke. As such, poor neurological outcome following beach chair positioning is a growing concern. In the proposed study the investigators test the hypothesis that changes in ventilation strategy and anesthetic technique can affect cerebral oxygenation in anesthetized patients in the beach chair position.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsStroke
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedFeb 17, 2012
Enrollment StartSep 1, 2012
Primary CompletionSep 1, 2014
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 14.4 years ago

Interventions

Inspired oxygen fraction / end tidal carbon dioxideother

Following induction of anesthesia, FIO2 and minute ventilation will be sequentially adjusted to achieve: 1. FIO2 30% (70% nitrogen), PETCO2 30mmHg - supine position. 2. FIO2 30% (70% nitrogen), PETCO2 30mmHg - beach chair position. 3. FIO2 100%, PETCO2 30mmHg - beach chair position. 4. FIO2 100%, PETCO2 45mmHg - beach chair position. 5. FIO2 30% (70% nitrogen), PETCO2 30mmHg - beach chair position.