CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 42 enrolled
Drug / intervention
SPWCV+Alum 100 mcg +3 morebiological
Likely dose
SPWCV+Alum 100 mcgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01537185
NCT01537185Phase 1Completed

A Phase 1 Randomized, Double-Blind, Dose-Escalation Study to Assess the Safety, Tolerability and Immunogenicity of Inactivated Streptococcus Pneumoniae Whole Cell Vaccine Formulated With Alum (SPWCV+Alum) in Healthy Adults

PATH Vaccine Solutions·interventional·Posted Feb 23, 2012·Updated Jun 5, 2014

In Brief

A Phase 1 clinical trial evaluating Placebo, SPWCV+Alum 100 mcg, and 2 other interventions for Pneumococcal Vaccines. Completed, enrolled 42 participants across 1 site.

Detailed Summary

The purpose of this study is to determine if a Streptococcus pneumoniae Whole Cell Vaccine (SPWCV) given with alum is safe and well tolerated by healthy adults.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedFeb 23, 2012
Enrollment StartFeb 1, 2012
Primary CompletionOct 1, 2012
Study CompletionApr 1, 2013
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 14.4 years ago

Interventions

Placeboother

3 cohorts of normal saline injection

SPWCV+Alum 100 mcgbiological

3 injections 28 days apart

SPWCV+Alum 600 mcgbiological

3 injections 28 days apart

SPWCV+Alum 300 mcgbiological

3 injections 28 days apart