CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 target
Drug / intervention
escitalopram oxalate +3 moredrug
Likely dose
escitalopram oxalate 10 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01538693
NCT01538693N/ACompleted
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Molecular Markers of Neuroplasticity During High-Intensity Exercise in Subjects With Incomplete Spinal Cord Injury

T. George Hornby·interventional·Posted Feb 24, 2012·Updated May 19, 2015

In Brief

A clinical study evaluating escitalopram oxalate, Cyproheptadine, and 2 other interventions for Spinal Cord Injury. Completed, enrolled 30 participants across 1 site.

Detailed Summary

The purpose of this study is to determine whether exercising (walking) at different intensities increases levels of factors in the blood and saliva that are known to impact neuroplasticity (how the connections in the spinal cord and brain can change) and if these levels are changed by pairing exercise with a single dose of commonly used prescription drugs or by your mood.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSpinal Cord Injury
CountriesUnited States
CollaboratorsUniversity of Medicine and Dentistry of New Jersey, Shirley Ryan AbilityLab

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedFeb 24, 2012
Enrollment StartDec 1, 2011
Primary CompletionMay 1, 2015
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 14.4 years ago

Interventions

escitalopram oxalatedrug

10 mg 4.5 hours prior to testing

Cyproheptadinedrug

8mg 4.5 hours prior to testing

sugar pilldrug

4.5 hour prior to testing

Graded intensity exerciseother

modified bruce protocol for peak oxygen consumption testing