CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 134 enrolled
Drug / intervention
Prolonged Exposure for PTSD (PE) + Treatment as Usual (TAU) +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01542229
NCT01542229N/ACompleted

Improving PTSD Service Delivery for Veterans With Severe Mental Illness

VA Office of Research and Development·interventional·Posted Mar 2, 2012·Updated Jul 15, 2019

In Brief

A clinical study evaluating Prolonged Exposure for PTSD (PE) + Treatment as Usual (TAU) and Treatment As Usual (TAU) for Post Traumatic Stress Disorder and 4 related conditions. Completed, enrolled 134 participants across 1 site.

Detailed Summary

As in the general population, there is no clear standard of care within Veterans Affairs Medical Centers for treating posttraumatic stress disorder (PTSD) among individuals with severe mental illness (SMI). This is a considerable issue because trauma, posttraumatic stress disorder (PTSD), and severe psychiatric comorbidity are particularly common among Veterans and this symptom presentation clearly exacerbates the overall course and severity of mental illness. This study is significant in that it proposes to establish the efficacy of a frontline exposure based intervention for posttraumatic stress disorder (PTSD), Prolonged Exposure, for improving critical clinical, quality of life, and cost outcomes among Veterans with severe mental illness (SMI) enrolled in VA healthcare. Collectively, it is anticipated that these data will establish a much needed clinical course of action for what is considered a vulnerable yet highly underserved patient population.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedMar 2, 2012
Enrollment StartMay 3, 2012
Primary CompletionDec 31, 2016
TodayJul 2, 2026
Enrollment to primary: 4.7 yearsPosted 14.3 years ago

Interventions

Prolonged Exposure for PTSD (PE) + Treatment as Usual (TAU)behavioral

12 weekly sessions of Prolonged Exposure in addition to Treatment As Usual

Treatment As Usual (TAU)behavioral

Treatment as usual (TAU) will receive support services through the VA potentially inclusive of case management, psychotropic medication management, and/or supportive counseling