At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effect of Low-Dose Dexamethasone on the Incidence of Hyperglycemia Following Surgery
In Brief
A Phase 4 clinical trial evaluating Control-saline, Dexamethasone 4 mg, and 2 other interventions for Postoperative Complications. Completed, enrolled 200 participants across 1 site.
Detailed Summary
The question of a possible hyperglycemic effect from single-dose dexamethasone is an important issue for clinicians managing patients in the intraoperative and postoperative periods. Recent evidence suggests that even moderate elevations in blood glucose levels may be associated with adverse events. The aim of this clinical investigation is to determine whether standard clinical doses of dexamethasone produce hyperglycemia in the perioperative period.
Study Details
Timeline
Interventions
Patients are randomized to receive saline 2 cc
Patients randomized to receive dexamethasone 4mg and 1 cc saline
Patients randomized to receive dexamethasone 8mg
Patients are randomized to receive saline 2 cc
Patients are randomized to receive dexamethasone 4 mg and saline 1 cc
Patients are randomized to receive dexamethasone 8 mg