At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized Comparison of Twice-Daily Versus Once-Daily Asenapine for Schizophrenia
In Brief
A Phase 4 clinical trial evaluating Asenapine 10 mg daily in the evening and Asenapine 5 mg twice daily for Schizophrenia. Completed, enrolled 30 participants across 1 site.
Detailed Summary
The investigators propose to explore: 1. the acceptance by patients of once versus twice daily dosing with asenapine, 2. the acceptance by staff of once versus twice daily dosing with asenapine, and 3. the changes in psychopathology associated with these two dosing strategies, in 30 patients with schizophrenia or schizoaffective disorder. The investigators hypothesize that patient and staff acceptance will be better with once daily dosing and that improvements in psychopathology will be similar across once daily and twice daily dosing
Study Details
Timeline
Interventions
The total daily dose of Asenapine will be given once daily in the evening
Asenapine will be given in two doses, 5 mg in the morning and 5 mg in the evening, daily