CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 230 enrolled
Drug / intervention
Western therapy (mannitol, methylprednisolone, immunoglobulin, febrifuge) +1 moredrug
Likely dose
Western therapy (mannitol, methylprednisolone, immunoglobulin, febrifuge) 1.0gfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01554930
NCT01554930N/ACompleted
CompareCT.gov

A Clinical Trial to Evaluate the Effectiveness and Safety of Chinese Medicine in the Treatment of Severe Type of Hand, Foot, and Mouth Disease

Jiangxi Qingfeng Pharmaceutical Co. Ltd.·interventional·Posted Mar 15, 2012·Updated Mar 15, 2012

In Brief

A clinical study evaluating Western therapy (mannitol, methylprednisolone, immunoglobulin, febrifuge) and Xiyanping injection plus western therapy for Hand, Foot, and Mouth Disease. Completed, enrolled 230 participants across 3 sites.

Detailed Summary

The study is aimed to evaluate the effectiveness and safety of Xiyanping injection,a traditional Chinese medicine (TCM), in the treatment of severe type of hand, foot, and mouth disease (HFMD).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHand, Foot, and Mouth Disease
CountriesChina
CollaboratorsChina Academy of Chinese Medical Sciences, Beijing YouAn Hospital, The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Beijing University of Chinese Medicine

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedMar 15, 2012
Enrollment StartMay 1, 2010
Primary CompletionNov 1, 2010
Study CompletionDec 1, 2011
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 14.3 years ago

Interventions

Western therapy (mannitol, methylprednisolone, immunoglobulin, febrifuge)drug

Mannitol:0.5-1.0g/kg，q4h to q8h ivgtt; Methylprednisolone:1mg-2mg/kg·d,qd iv; Immunoglobulin：1g/kg; Others:febrifuge，sedative，etc.

Xiyanping injection plus western therapydrug

Xiyanping injection:5-10mg/kg/d (0.2-0.4ml/kg/d),qd ivgtt; Mannitol:0.5-1.0g/kg，q4h to q8h ivgtt; Methylprednisolone:1mg-2mg/kg·d,qd iv; Immunoglobulin：1g/kg; Others:febrifuge，sedative，etc.